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Derma5D | Ultra Serum

Visible Skin Tightening + Hydration Serum

  • Instantly Tightens + Firms Skin 
  • Deeply Hydrates for Smoother, Plumper Skin 
  • Reduces the Look of Fine Lines + Wrinkles 
Choose Your Routine: Ultra Serum
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A New Dimension of Skincare Science

Most skincare is designed to target one concern at a time — hydration, firmness, or the appearance of wrinkles. 

But skin changes across multiple interconnected factors. 

Derma5D™ is designed to support skin more intelligently, addressing the key elements that influence how skin looks, feels, and functions over time. Using a combination of advanced bio-actives and clinically studied ingredients, this formula takes a more complete approach to visible skin renewal—supporting hydration, structure, elasticity, and overall skin quality together. 

5D Results. Clinically Measured.

Supports visibly smoother, more hydrated, and refined-looking skin across key dimensions of skin quality.*

+27%

Improved Skin Hydration + Glow

-26%

Wrinkle Surface Decrease

Meet the Visible Renewal System

Get more out of your routine by pairing Derma5D™ and Collagen5D™ — a complete inside-out approach designed to improve hydration, firmness, overall skin quality.

Frequently Asked Questions

Overall rating: 4.8157897 / 5 from 38 reviews.

AI Generated Review Summary

Derma5D™ Ultra Serum is praised for its ability to enhance skin firmness, hydration, texture, and reduce fine lines. Customers report noticeable improvements in skin appearance and feel, with many noting a healthier and more radiant look after use.

Summary topics

  • Skin Hydration: 76%
  • Customer Satisfaction: 20%
  • Noticeable Skin Improvement: 20%
  • Skin Feel: 20%
  • Hydration System: 32%

Review topics: ["improvement","smell","feeling","felt","skin","looks","hydration","difference","results","face","serum","system","capsules","pills","moisturizer","addition","change","aftertaste","noticed","lines"].

Review highlights

  • "I noticed results in my face right away, the fine lines have lightened and my skin just feels tighter."Sarah
  • "Upon the first application my skin felt so soft and smooth…no sticky, greasy feeling at all."Zde0007
  • "My skin looks healthier, feels more hydrated, and I love the added benefits I've seen with my hair and nails."StephC

Reviews

Great hydration!

"I have sensitive dry skin and am really happy with this! The serum is light, smooth, and melts right into my skin. Smell is very light (almost cucumber-ish). I could definitely notice the extra hydration throughout the day. Not sure if I could notice the collagen supplement results yet, but it has only been a short time. Can’t wait to see how they improve my skin over time!"

Meg S. (5/5)

Was skeptical, but not anymore!

"I truly was skeptical about this product. I always am actually on trying a new product, but this really delivered on what I was looking to get out of it. My skin used to be dry & flaky, especially at my age. This serum was amazing! Not only was my face hydrated, it felt smooth to the touch. The smell is very light and pleasant. It didn't leave my face greasy at all. I even used it on my hands which were always dry and it helped a lot!"

Cynthia M. (5/5)

Great product

"Visual results and you can see the improvement taking both products together - fair warning that the capsules are pretty big for those who dont like swallow pills. The serum is easy to apply with a light scent. It firms my skin pretty well. I love how it hydrated my skin. this is a dual system it was nice to trust they both work together. it doesnt get greasy and all it reduced the redness"

jess p. (5/5)

Radiance in a Bottle and a Capsule

"Glowing From the Inside Out I've been using serum along with the capsules, and I have truly enjoyed incorporating them into my skincare routine. The serum feels lightweight and absorbs nicely into my skin, leaving it feeling soft and hydrated without being greasy. Pairing it with the capsules makes me feel like I'm supporting my skin from both the outside and the inside. Over time, my skin has felt smoother, healthier, and more radiant. If you're looking for a simple addition to your skincare routine, may be worth trying."

LaShawn B. (5/5)

have to be consistent

"this is my first time taking collagen and really taking care of my skin on my face. So far its been great. I did notice after i wake up my skin feels softer. The key is to keep up with consistent applications and taking the pills. i would buy it again"

Andrei L. (4/5)

Great feeling skin

"Can’t believe how much i love this serum! My skins feels softer, brighter & more hydrated. I highly recommend this product if your looking for something To make you feel young again !"

Katelynn D. (5/5)

Ok on serum

"The serum is easy to use , spreads nicely . However the smell is not great but does seem to firm up the skin"

Avis (3/5)

Lightweight but super moisturizing

"I use the lotion twice a day and can see a slight difference in my skin so far. Its only been a few weeks but it definitely does what it's intended to do. Very happy with this product so far."

Diane T. (5/5)

Hydration without the grease!

"I've been using the Derma5D Visible Renewal System as part of my nightly skincare routine, and it's quickly become one of my favorite products. The biggest difference I've noticed is how hydrated my skin feels when I wake up in the morning. My face looks softer, more refreshed, and has a healthy glow that lasts throughout the day. After consistent use, I've also noticed my skin feels firmer and more resilient, especially around areas where I tend to see the first signs of aging. The combination of inside and outside support makes it feel like I'm doing something truly beneficial for my skin rather than just applying another moisturizer. If you're looking for a product that supports hydration, improves the appearance of firmness, and helps your skin look healthier over time, I highly recommend adding Derma5D Visible Renewal to your routine."

shaun (5/5)

Hydrated & healthy

"I’ve been using this serum for 4 weeks now and have noticed a significant improvement in my skin’s hydration and how healthy it’s looking."

Kara (5/5)

Q&A

MyBiotin® ProClinical is crafted with the highest standards in mind. Every batch is lab-tested for purity and potency to ensure you get the nutrients your hair and skin need. We use only clinically studied ingredients in precise, effective doses — because real results start with real science. Plus, it’s free from artificial fillers, colors, and animal by-products, so you can feel confident about every serving.